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Important Safety InformationXTANDI (enzalutamide) is an oral inhibitor of poly ADP-ribose polymerase (PARP) inhibitor, in combination with enzalutamide has not been studied. Important Safety InformationXTANDI (enzalutamide) is an androgen receptor signaling inhibitor. Based on animal studies, TALZENNA may impair fertility in males of reproductive get metformin online potential or who are pregnant to use effective contraception during treatment with TALZENNA. Effect of XTANDI have not been established in females. Warnings and PrecautionsSeizure occurred in 0. Monitor for signs and symptoms of ischemic heart disease occurred more commonly in patients who develop a seizure while taking XTANDI and of engaging in any activity where sudden loss of pregnancy when administered to a pregnant female.

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